Dectin-1-mediated pain is critical for the resolution of fungal inflammation

Dectin-1-mediated pain is critical for the resolution of fungal inflammation

Candidiasis is a painful infection that affects a large number of individuals, occasionally causing severe pain that is solely controlled by resolution of infection. Here, Dectin-1 inhibition was found to block pain during fungal infection. Researchers found that clodronate, a drug that is currently used for osteoporosis treatment, could suppress severe pain in fungal infection, and that the Dectin-1 pathway could be an important new target for treatment of pain.
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https://www.sciencedaily.com/releases/2018/08/180829115552.htm